Important Safety Information

The most common adverse reaction reported is vomiting.

Other adverse reactions reported in decreasing order of frequency are: depression/lethargy, decreased appetite, incoordination, diarrhea, itching, trembling, excessive salivation and seizures.

Following concomitant extra-label use of ivermectin with Comfortis, some dogs have experienced the following clinical signs: trembling/twitching, salivation/drooling, seizures, incoordination, excessive dilation of pupils, blindness and disorientation.

Post-approval experience continues to support the safety of Comfortis when used concurrently with heartworm preventatives according to label directions.

View full product label for complete safety information.

References

1. Ipsos Forward Research January 2011: Veterinarians

2. The Presidential Green Chemistry Challenge Awards Program, Summary of 1999 Award Entries and Recipients