Comfortis^® (spinosad)

Click here for a printable version of the client information sheet (PDF).

Important Safety Information

• The most common adverse reaction reported is vomiting.
• Other adverse reactions reported in decreasing order of frequency are: depression/lethargy, decreased appetite, incoordination, diarrhea, itching, trembling, excessive salivation and seizures.
• Following concomitant extra label use of ivermectin with Comfortis, some dogs have experienced the following clinical signs: trembling/twitching, salivation /drooling, seizures, incoordination, excessive dilation of pupils, blindness and disorientation.
• Post approval experience continues to support the safety of Comfortis when used concurrently with heartworm preventatives according to label directions.
• Click here for full product label including complete safety information.