The active ingredient in Comfortis™ is spinosad. When ingested by fleas, spinosad targets the flea’s nervous system, causing the flea to show involuntary muscle contraction and tremors. Spinosad-induced excitation leads to flea paralysis and rapid death.
While extremely toxic to fleas, spinosad does not affect the mammalian nervous system. Dogs do not have the same response to Comfortis™.
Because you give Comfortis to your pet orally, you do not have to tolerate the mess and inconvenience of topical pesticides. Comfortis is rapidly absorbed in your dog’s bloodstream, where it circulates and protects your dog from flea infestation for a full month. Comfortis begins killing fleas within 30 minutes, so you know your dog is getting fast relief and long-lasting protection.
Comfortis does not depend on your dog’s skin and hair coat to distribute across the body. That’s why Comfortis is a great choice for dogs with skin problems, as flea protection is vitally important and cannot be compromised.
The most common adverse reaction recorded during clinical trials was vomiting. Other adverse reactions were decreased appetite,
lethargy, redness of the skin, hyperactivity and excessive salivation. Click here for
important safety information and full product label (PDF).
